Serum Proteomic Profiling Implicates a Dysregulated Neurohormonal-Inflammatory Axis in Post-Fontan Tachycardia
Felipe Takaesu, Delaney J Villarreal, Ashley Zhou, Michael R. Jimenez, Mackenzie E. Turner, Joshua Spiess, Jennifer C. Kievert, Cameron M. DeShetler, William E. Schwartzman, Andrew R. Yates, John M. Kelly, Christopher K. Breuer, Michael E. Davis
This study uses serum proteomics and machine learning to identify a seven-protein panel predictive of post-Fontan tachycardia, implicating a dysregulated neurohormonal-inflammatory axis.
bioRxiv · Feb 2, 2026 · PreprintBioinformatics