Author

John M. Kelly

Nationwide Children's HospitalORCID 0000-0002-5865-5347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Assay:long-read sequencing· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley Zhou· 2 shared Christopher K. BreueriD· 2 shared Felipe TakaesuiD· 2 shared Jennifer C. KievertiD· 2 shared Michael E. DavisiD· 2 shared Adrienne Morrison· 1 shared Andrew R. YatesiD· 1 shared Aymen NaguibiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Ashley Zhou

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Author profile →

2 papers

Recent·Most cited

The Fontan EV Score: A Circulating Extracellular Vesicle-Based Risk Stratification Tool for Fontan-Associated Liver Disease

Felipe Takaesu, Xinlei Li, Jennifer C. Kievert, Ashley Zhou, Sherri Kemper, Satoshi Yuhara, Syed Hussain, Tatsuya Watanabe, Matsuda Junya, Fahd Taha, Adrienne Morrison, Kirsten Nelson, Jocelyhnn Zucco, Aymen Naguib, Christopher T. McKee, , Michael E. Davis

This paper develops the Fontan EV Score, a non-invasive biomarker using circulating extracellular vesicles to predict Fontan-associated liver disease severity, outperforming existing serological indices.

bioRxiv · Aug 4, 2026 · PreprintBioinformatics

Serum Proteomic Profiling Implicates a Dysregulated Neurohormonal-Inflammatory Axis in Post-Fontan Tachycardia

Felipe Takaesu, Delaney J Villarreal, Ashley Zhou, Michael R. Jimenez, Mackenzie E. Turner, Joshua Spiess, Jennifer C. Kievert, Cameron M. DeShetler, William E. Schwartzman, Andrew R. Yates, John M. Kelly, Christopher K. Breuer, Michael E. Davis

This study uses serum proteomics and machine learning to identify a seven-protein panel predictive of post-Fontan tachycardia, implicating a dysregulated neurohormonal-inflammatory axis.

bioRxiv · Feb 2, 2026 · PreprintBioinformatics