Targeted editing of pericentromeric satellite DNA alters sensitivity to meiotic drive
Danna G. Eickbush, Jabale Rahmat, Matthew Lindsay, Josiah Bowers, Nicholas J. Fuda, Amanda M. Larracuente
This study uses CRISPR/Cas9 to edit pericentromeric satellite DNA in Drosophila and shows that copy number affects sensitivity to a meiotic drive system.
bioRxiv · Jan 21, 2026 · PreprintGenetics