RasGRP1 Signalling Programs Developing γδ-Thymocytes towards the γδT17 Lineage Through Control of c-Maf Expression
Kevin Joannou, Dominic P. Golec, Abul Kalam Azad, Laura M. Henao Caviedes, Julia F May, Ress G Kelly, Troy A. Baldwin
This study shows RasGRP1 is essential for generating CD73+ γδ T cells and regulating c-Maf expression to drive γδT17 lineage commitment.
The Journal of Immunology · Sep 1, 2025Peer-reviewedImmunology