Disrupted Transcriptional Networks by Mutant Atrophin-1 in a Cell Culture Model of Dentatorubral-Pallidoluysian Atrophy
Oluwademilade Nuga, Masoumeh Pourhadi, Julia P. Rausch, Sokol V. Todi
This study uses RNA-seq to analyze transcriptomic changes in HEK293T cells with mutant Atrophin-1, identifying disruptions in multiple pathways linked to DRPLA pathology.
bioRxiv · Aug 8, 2025 · PreprintNeuroscience