MicrobiologybioRxivPreprint
Positive selection analyses identify a single WWE domain residue that shapes ZAP into a super restriction factor
Serina Huang, Juliana Girdner, LeAnn P Nguyen…·Melody MH Li
This study identifies a single residue in ZAP's WWE domain that enhances its antiviral activity against alphaviruses by improving viral translation inhibition.
DOI 10.1101/2023.11.20.567784