Melody M. H. Li

SARS-CoV-2 nucleocapsid induces hyperinflammation and vascular leakage through the Toll-like receptor signaling axis in macrophages

This study shows the SARS-CoV-2 nucleocapsid protein drives hyperinflammation and vascular leakage in macrophages via Toll-like receptor signaling, contributing to severe COVID-19 complications.

Programmable artificial RNA condensates in mammalian cells

This paper introduces programmable artificial RNA condensates in mammalian cells that can be controlled for subcellular localization and molecular recruitment.

Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion

This study identifies SLC2A3 as a key factor for Old World alphavirus neuroinvasion through BBB infection, revealing a conserved mechanism across multiple viruses.

Global Landscape of Human Kinase Motifs in Viral Proteomes

The paper identifies human kinase motifs in viral proteomes, showing enrichment for stress and immune-related kinases and their phosphorylation in infected cells.