Functional diversity of Vγ9Vδ2 T cells overcomes glioblastoma state plasticity and antigen heterogeneity
Pierre Paris, Marine Devinat, Julianne Ceroni, Elodie Guiet, Jocelyn Ollier, Mélanie Laurent—Blond, Pauline Thomas, M. Gaudin, Noémie Joalland, A. Perrin, Clément Philippe Delannoy, Audrey Rousseau, Philippe Meneï, Emmanuel Scotet, François Paris, , Claire Pecqueur
This study shows that combining GD2/OAcGD2-specific CAR and unmodified Vγ9Vδ2 T cells can overcome glioblastoma heterogeneity by targeting both PN and MES tumor states.
bioRxiv · May 21, 2026 · PreprintCancer Biology