Profiling telomere content and composition at single-cell resolution incancer and immune cells
Niklas L Engel, Hanna Friess, Julia Grigorjew, Ferdinand Popp, Lea Herzel, Binnur Özay, Julie Surmely, Malte Simon, Charles David Imbusch, Benedikt Brors, Lars Feuerbach
This paper develops a computational framework to quantify telomere content and composition from scATAC-seq data, revealing patient-specific telomere maintenance patterns in cancer and immune cells.
bioRxiv · Aug 28, 2024 · PreprintCancer Biology