Niklas L Engel

This study uses Nanopore whole-genome sequencing to show conserved chromosome-specific telomere length patterns across tissues and populations, revealing coordinated regulation and potential disease risk factors.

This study shows SPT5 regulates Pol II pausing and elongation differently in early and late Drosophila embryogenesis, affecting gene expression dynamics.

This paper develops a computational framework to quantify telomere content and composition from scATAC-seq data, revealing patient-specific telomere maintenance patterns in cancer and immune cells.