Scalable Inference and Identifiability of Kinetic Parameters for Transcriptional Bursting from Single Cell Data
Junhao Gu, Nandor Laszik, Christopher E. Miles, Jun F. Allard, Timothy L. Downing, Elizabeth L. Read
This paper develops a computational pipeline to infer kinetic parameters from single-cell RNA sequencing data and assesses parameter identifiability using the stochastic telegraph model.
Bioinformatics · Oct 18, 2025Peer-reviewedBiophysics