Spontaneous peripheral oxygen desaturation and apnea events in mice vary by strain and inspired oxygen level
Hardik Kalra, Anastasiia Vasileva, Charles R. Jedlicka, Mikhail Vasilyev, Michelle A. Buckman, Zishan Zhang, Brian K. Gehlbach, Junjie Liu, Lara Roberts DeRuisseau, Mark W. Chapleau, Patrick John Breheny, Michael H. Tomasson, Melissa Lowe Bates
This study shows that mice experience spontaneous oxygen desaturations and apneas that vary by strain and inspired oxygen level, with desaturations often not linked to apneas.
bioRxiv · Sep 1, 2025 · PreprintPhysiology