YY1-Mediated Polycomb Group Function Safeguards Hematopoietic Stem Cells from Premature Aging
Sahitya Saka, Junki P. Lee, Yinghua Wang, Peng Liu, Yunxia Liu, Courtney C. Hong, Ashley M. Kuehnl, Lixin Rui, Michael L. Atchison, Xuan Pan
This study shows that YY1's Polycomb group function is essential for maintaining HSC quiescence and preventing premature aging.
bioRxiv · Jan 29, 2026 · PreprintMolecular Biology