Targeting von Willebrand factor selectively under inflammatory conditions
Gianluca Interlandi, Victoria S. Carter, Yi Wang, Alexander St. John, Jennie Le, Junmei Chen, José A. López, Xiaoyun Fu
This study develops an assay to test drugs that inhibit von Willebrand factor selectively under oxidizing inflammatory conditions, finding lumacaftor may do so effectively.
bioRxiv · Aug 13, 2025 · PreprintBiochemistry