The NuRD complex shapes RNA polymerase III activity at highly expressed tRNA gene clusters, tuning the dynamic range of cellular tRNA pools
Ruiying Cheng, K C Rajendra, Simon Lizarazo, Junmeng Yuan, Sihang Zhou, Kevin Van Bortle
The paper identifies NuRD complex interactions with Pol III and shows NuRD regulates Pol III activity at highly expressed tRNA gene clusters, modulating tRNA pool dynamics.
bioRxiv · Dec 13, 2025 · PreprintMolecular Biology