Ruiying Cheng

The paper uses effective conductance to infer protein-protein relationships and identifies network hubs and macromolecular interactions using a new tool called CoBRAA.

The paper creates a Pol III activity atlas across tissues and cancers, revealing context-specific expression patterns and linking them to subnuclear compartmentalization.

The paper identifies NuRD complex interactions with Pol III and shows NuRD regulates Pol III activity at highly expressed tRNA gene clusters, modulating tRNA pool dynamics.

The paper investigates snaR-A, a cancer-associated ncRNA, showing it interacts with splicing factors and disrupts mRNA processing, contributing to cancer progression.

The paper identifies widespread Pol III recruitment to protein-coding gene promoters, revealing novel small ncRNAs and functional implications for gene regulation and cancer.