Self-Supervised Representation Learning of Protein Tertiary Structures (PtsRep) and Its Implications for Protein Engineering
Junwen Luo, Yi Cai, Jialin Wu, Hongmin Cai, Xiaofeng Yang, Zhanglin Lin
PtsRep, a self-supervised framework for learning protein tertiary structure representations, outperforms existing methods in predicting protein stability and GFP fluorescence brightness.
bioRxiv · Dec 22, 2020 · PreprintBioinformatics