Modeling Reactive Species Metabolism in Colorectal Cancer for Identifying Metabolic Targets and Devising Therapeutics
Prerna Bhalla, Subasree Sridhar, Justin Kullu, Sriya Veerapaneni, Swagatika Sahoo, Nirav Bhatt, Gadi K. Suraishkumar
This paper develops a reactive species module for genome-scale metabolic models to identify metabolic targets in colorectal cancer and highlights ferroptosis as a therapeutic target.
bioRxiv · May 3, 2022 · PreprintSystems Biology