Swagatika Sahoo

This paper develops a reactive species module for genome-scale metabolic models to identify metabolic targets in colorectal cancer and highlights ferroptosis as a therapeutic target.

The paper investigates how silver nanoparticles induce oxidative stress in gut bacteria, increasing folic acid production, which reduces colon cancer cell viability.

The paper introduces the Virtual Metabolic Human database, which integrates human and gut microbiome metabolism with nutrition and disease data to support biomedical research.

The paper develops an integrated computational model to explore how diet and gut microbiota interact in autism, showing probiotics reduce oxidative stress and microbiome-diet interactions affect host metabolism.

The paper presents two gender-specific whole-body metabolism models, Harvey and Harvetta, that integrate physiological and omics data to predict metabolic processes and interactions across organs.