Author

Justin Petucci

Pennsylvania State University

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Biology Disciplines

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Biophysics· 1

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Organism:E. coli· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Edward P. O’BrieniD· 1 shared Hyebin SongiD· 1 shared Ian M. SitarikiD· 1 shared Pilar FrutosiD· 1 shared Quyen V. VuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Edward P. O’BrienORCID

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1 paper

Recent·Most cited

A widespread protein misfolding mechanism is differentially rescued by chaperones based on gene essentiality

Ian M. Sitarik, Quyen V. Vu, Justin Petucci, Pilar Frutos, Hyebin Song, Edward P. O’Brien

The paper identifies a widespread protein misfolding mechanism involving non-covalent lasso entanglement (NCLE) and shows that chaperones rescue it more effectively for essential proteins.

bioRxiv · Sep 18, 2025 · PreprintBiophysics