Predicting FDA approvability of small-molecule drugs
Chih-Han Huang, Justine Hsu, Li-yen Yang, Tsai‐Min Chen, Edward S.C. Shih, Ming‐Jing Hwang
This paper develops machine learning models to predict small-molecule drug FDA approvability and clinical trial success using molecular structure and physicochemical properties, significantly reducing attrition rates.
bioRxiv · Oct 15, 2022 · PreprintBioinformatics