Time-dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal
Sudeep Mehrotra, Haven Jeanneret, Kristin M. Perkumas, Renee Liu, Jyoti Lama, Katie Huynh, Ananya Mukundan, Hilary A. Scott, Atitaya Apivatthakakul, Janey L. Wiggs, Lucia Sobrin, William Daniel Stamer, Ayellet V. Segrè
This study identifies glucocorticoid-induced transcriptomic changes in human trabecular meshwork and Schlemm's canal cells using RNA-seq, finding genes associated with glaucoma and intraocular pressure.
bioRxiv · Jan 1, 2026 · PreprintGenomics