ETV7 regulates breast cancer stem-like cell plasticity by repressing IFN-response genes
L. Pezze, M. Forcato, S. Pontalti, K. A. Badowska, D. Rizzotto, I.-I. Skvortsova, S. Bicciato, Y. Ciribilli
This study shows ETV7 promotes breast cancer stem-like cell plasticity and resistance to chemotherapy and radiotherapy by repressing IFN-response genes, which may be reversible with IFN-β treatment.
bioRxiv · Sep 2, 2020Cancer Biology