The Role of Binding Site Specificity in the Disaggregation of Aβ42 Fibrils through a Synthetic Paratope
S. Tiwari, B. Mandal, K. Anki Reddy
This study uses molecular dynamics simulations to investigate how a synthetic paratope binds to and disrupts Aβ42 protofibrils, revealing key interactions that could inform drug development for Alzheimer's disease.
bioRxiv · Aug 11, 2023 · PreprintBiophysics