ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expression
A. Sinha, K. K. Saini, K. Tripathi, M. A. Khan, S. R. Satrusal, A. Verma, B. Mandal, P. Rai, S. Meena, M. A. Nengroo, M. P. Singh, N. S. Bhushan, M. Vasudevan, A. Singhai, K. Singh, , D. Datta
This study identifies ACSL4 as a driver of TNBC metastasis by enhancing histone acetylation and SNAIL expression through metabolic and epigenetic mechanisms.
bioRxiv · Oct 16, 2023 · PreprintCancer Biology