Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development
K. Matsumoto, K. B. Luther, R. S. Haltiwanger
The paper analyzes O-fucose modification on NOTCH1 in POFUT1 S162L patient fibroblasts and finds reduced ligand binding and absence of O-fucose at EGF12.
bioRxiv · Apr 9, 2024 · PreprintBiochemistry