Cationic charge and polyspecificity of an integrin domain regulates infectivity of malaria parasites
D. Klug, S. Goellner, J. Sattler, L. Strauss, J. Kehrer, K. Beyer, M. Reinig, M. Singer, C. Lu, T. A. Springer, F. Frischknecht
This study shows that the I-domain of TRAP in Plasmodium parasites mediates adhesion and that its cationic charge and polyspecificity are critical for infectivity.
bioRxiv · Sep 20, 2018 · PreprintMicrobiology