Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis
E. J. Schuster, N. K. Dashzeveg, Y. Jia, K. Golam, T. Zhang, A. D. Hoffman, Y. Zhang, C. Zheng, E. K. Ramos, R. Taftaf, L. El-Shennawy, D. Scholten, V. Adorno-Cruz, C. Reduzzi, R. Xu, , S. Spahija
This study identifies Plexin-B2 as a driver of homotypic and heterotypic CTC clusters in breast cancer metastasis, with high expression linked to poor prognosis and therapeutic potential.
bioRxiv · Apr 10, 2023 · PreprintCancer Biology