Novel RNA m6A methyltransferase METTL16 inhibitors
S. Selberg, L. Ivanova, M. Kotli, K. Herodes, D. Blokhina, E. Kankuri, N. Seli, I. Ilves, I. Teino, M. Saarma, M. Karelson
This study identifies two nanomolar METTL16 inhibitors that reduce leukemia cell viability and m6A levels in HL-60 cells.
bioRxiv · Mar 27, 2023 · PreprintPharmacology & Toxicology