Spatial transcriptomics of tumor microenvironment in formalin-fixed paraffin-embedded breast cancer
L. Romanens, P. Chaskar, J.-C. Tille, S. Ryser, N. Liaudet, K. Hu-Heimgartner, K. Heimgartner, G. Kaya, P. Tsantoulis, S. I. Labidi-Galy
This study develops a method for RNA sequencing of laser-capture microdissected cells from FFPE breast cancer samples, revealing distinct gene expression profiles between tumor cells and immune cells.
bioRxiv · Jan 31, 2020 · PreprintCancer Biology