Author

P. Tsantoulis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. D. Campbell· 1 shared A. Easton· 1 shared A. K. Najumudeen· 1 shared A. M. B. McCorry· 1 shared C. Larrue· 1 shared C. Recher· 1 shared D. J. Flanagan· 1 shared D. J. Huels· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. D. Campbell

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3 papers

Recent·Most cited

Ferritinophagy is a Druggable Vulnerability of Quiescent Leukemic Stem Cells

C. Larrue, S. Mouche, P. Angelino, M. Sajot, R. Birsen, F. Vergez, C. Recher, V. Mansat-De Mas, Q. Gu, J. Xu, P. Tsantoulis, J.-E. Sarry, J. Tamburini

The paper identifies ferritinophagy as a therapeutic target in quiescent leukemic stem cells, showing that inhibiting NCOA4 reduces leukemia.

bioRxiv · Dec 18, 2023 · PreprintCancer Biology

Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

E. Gil Vazquez, N. Nasreddin, G. N. Valbuena, E. J. Mulholland, H. L. Belnoue-Davis, H. Eggington, R. O. Schenck, V. M. Wouters, P. Wirapati, K. Gilroy, T. R. M. Lannagan, D. J. Flanagan, A. K. Najumudeen, S. Omwenga, A. M. B. McCorry, , S. J. Leedham

The paper examines stem cell population dynamics in colorectal tumors, showing that CBC-RSC admixture correlates with mutations and microenvironmental changes, and is linked to chemoresistance.

bioRxiv · Jun 11, 2022Cancer Biology

Spatial transcriptomics of tumor microenvironment in formalin-fixed paraffin-embedded breast cancer

L. Romanens, P. Chaskar, J.-C. Tille, S. Ryser, N. Liaudet, K. Hu-Heimgartner, K. Heimgartner, G. Kaya, P. Tsantoulis, S. I. Labidi-Galy

This study develops a method for RNA sequencing of laser-capture microdissected cells from FFPE breast cancer samples, revealing distinct gene expression profiles between tumor cells and immune cells.

bioRxiv · Jan 31, 2020 · PreprintCancer Biology