Author

K. J. O'Keefe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

D. A. Nelson· 3 shared M. Larsen· 3 shared A. L. Altrieth· 2 shared A. R. Stabell· 1 shared C. V. Cordi· 1 shared E. Z. M. Taroc· 1 shared J. C. Turrieta· 1 shared J. R. Tavarez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

D. A. Nelson

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 9, 2023

Identifying Fibrogenic Cells Following Salivary Gland Obstructive Injury

A. L. Altrieth, K. J. O'Keefe, V. A. Gellatly…·M. Larsen

This study investigates the role of Gli1+ cells in fibrosis following salivary gland injury, finding that they contribute minimally to fibrotic changes, while PDGFR+ stromal cells show fibrogenic potential.

DOI 10.1101/2023.03.09.531751

mousescRNA-seq

𝕏 PostBluesky

PathologybioRxivJul 29, 2019

Regional Differences Following Partial Salivary Gland Resection

K. J. O'Keefe, K. A. DeSantis, A. L. Altrieth…·M. Larsen

This study examines regional differences in wound healing and fibrotic responses after partial salivary gland resection in mice, identifying transient and sustained cellular and molecular changes.

DOI 10.1177/0022034519889026

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivJul 24, 2019

ROCK Inhibitor Increases Proacinar Cells in Adult Salivary Gland Organoids

M. H. Koslow, K. J. O'Keefe, D. A. Nelson, M. Larsen

This study shows that the ROCK inhibitor Y27632 increases Kit+ and K5+ cells in salisphere cultures and enhances the formation of salivary organoids expressing AQP5.

DOI 10.1016/j.scr.2019.101608

mouseorganoid / primary culture

𝕏 PostBluesky