K. Joron

PEG-mCherry interactions beyond classical macromolecular crowding

This study investigates PEG-induced structural and dynamical changes in mCherry using simulations and experiments, revealing specific PEG-mCherry interactions beyond classical crowding effects.

Fluorescent protein lifetimes report increased local densities and phases of nuclear condensates during embryonic stem cell differentiation

The paper uses fluorescent protein lifetimes to measure local densities in nuclear condensates during mouse embryonic stem cell differentiation, finding increased homogeneity in HP1 condensates post-differentiation.

Evidence for a compact apo-σ70 conformation in vitro and in vivo

The paper identifies a compact apo-σ70 conformation in vitro and in vivo using CL-MS, suggesting it may be transcriptionally inactive and activated upon RNAP binding.

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

This study maps the conformational space of α-synuclein monomer using simulations and experimental validations, revealing stable conformations with slow interconversion times.