K. Kapoor

Rapid and high yield isolation of extracellular vesicles with purity by application of size exclusion fast performance liquid chromatography.

This paper introduces a rapid and high-yield method for isolating extracellular vesicles with high purity, demonstrating its effectiveness across multiple sources and applications.

Post-Translational Modifications Optimize the Ability of SARS-CoV-2 Spike for Effective Interaction with Host Cell Receptors

This paper develops a full-length, membrane-bound SARS-CoV-2 spike model with post-translational modifications, revealing how glycosylation and palmitoylation enhance its conformational dynamics and interaction with host cell receptors.

Extended-Ensemble Docking to Probe Evolution of Ligand Binding Sites in Proteins Undergoing Large-Scale Structural Changes for Their Function

This paper introduces extended-ensemble docking to study ligand binding in P-glycoprotein, showing better agreement with experiments by considering multiple conformational states.

Active Participation of Membrane Lipids in Inhibition of Multidrug Transporter P-Glycoprotein

This study uses molecular dynamics simulations to show that tariquidar, a P-glycoprotein inhibitor, recruits lipids into the transporter's lumen, enhancing conformational restriction and inhibiting drug efflux.

Binding Mode of SARS-CoV2 Fusion Peptide to Human Cellular Membrane

This study uses molecular dynamics simulations to analyze how the SARS-CoV2 fusion peptide binds to human cell membranes, identifying three binding modes with the deepest penetration being the most biologically relevant.

A Single Nucleotide Polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated North American Cannabis

The paper uses SNP markers to analyze genetic diversity and population structure in North American Cannabis, identifying clusters linked to cannabinoid profiles and traits.