Raman Needle Arthroscopy for In Vivo Molecular Assessment of Cartilage
K. Kroupa, M. I. Wu, J. Zhang, M. Jensen, W. Wong, J. B. Engiles, M. W. Grinstaff, B. D. Snyder, M. S. Bergholt, M. B. Albro
This paper introduces a Raman needle arthroscopy technique to assess cartilage health in vivo by quantifying ECM biomarkers like GAG and collagen, showing high predictive accuracy in ex vivo models and demonstrating its first in vivo use.
bioRxiv · Jun 15, 2021Bioengineering