Author

M. W. Grinstaff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. M. McDermott· 1 shared A. Patwa· 1 shared B. D. Snyder· 1 shared C. H. Lo· 1 shared D. E. Mason· 1 shared D. J. Kelly· 1 shared D. Kenney· 1 shared E. Alsberg· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. M. McDermott

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Complete substitution with modified nucleotides suppresses the early interferon response and increases the potency of self-amplifying RNA

J. E. McGee, J. R. Kirsch, D. Kenney, E. Chavez, T.-Y. Shih, F. Douam, W. W. Wong, M. W. Grinstaff

This paper shows that complete substitution of nucleotides in self-amplifying RNA (saRNA) reduces interferon response and enhances expression, improving vaccine potency.

bioRxiv · Sep 15, 2023Bioengineering

Acidic nanoparticles restore lysosomal acidification and rescue metabolic dysfunction in pancreatic β-cells under lipotoxic condition

C. H. Lo, L. M. O'Connor, G. W. Z. Loi, E. N. Saipuljumri, J. Indajang, K. M. Lopes, O. S. Shirihai, M. W. Grinstaff, J. Zeng

This study develops TFSA nanoparticles that restore lysosomal acidification and improve metabolic function in pancreatic β-cells under lipotoxic conditions.

bioRxiv · Jul 11, 2023Bioengineering

Raman Needle Arthroscopy for In Vivo Molecular Assessment of Cartilage

K. Kroupa, M. I. Wu, J. Zhang, M. Jensen, W. Wong, J. B. Engiles, M. W. Grinstaff, B. D. Snyder, M. S. Bergholt, M. B. Albro

This paper introduces a Raman needle arthroscopy technique to assess cartilage health in vivo by quantifying ECM biomarkers like GAG and collagen, showing high predictive accuracy in ex vivo models and demonstrating its first in vivo use.

bioRxiv · Jun 15, 2021Bioengineering

Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues

A. M. McDermott, S. Herberg, D. E. Mason, H. B. Pearson, J. H. Dawahare, J. M. Collins, R. Tang, A. Patwa, M. W. Grinstaff, D. J. Kelly, E. Alsberg, J. D. Boerckel

This study shows that mechanical loading enhances bone regeneration through engineered mesenchymal condensations, mimicking endochondral ossification without heterotopic bone formation.

bioRxiv · Aug 15, 2018Bioengineering