Coiled coils 9-to-5: Rational de novo design of α-helical barrels with tunable oligomeric states
W. M. Dawson, F. J. Martin, G. G. Rhys, K. L. Shelley, R. L. Brady, D. N. Woolfson
This study designs α-helical barrels with tunable oligomeric states by modifying residue size in coiled-coil sequences, supported by X-ray crystal structures.
bioRxiv · Jan 20, 2021Biochemistry