Survivin in synergy with BAF/SWI complex binds bivalent chromatin regions and activates DNA damage response in CD4+ T cells
V. Chandrasekaran, K. M. E. Andersson, M. C. Erlandsson, S. Li, M.-J. Garcia-Bonete, E. Malmhall-Bah, P. Johansson, G. Katona, M. I. Bokarewa
This study shows survivin interacts with BAF/SWI complex at bivalent chromatin regions to repress DNA repair in IFNγ-stimulated CD4+ T cells, promoting autoimmune profiles.
bioRxiv · Mar 5, 2024Immunology