Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML
J. S. Smitth, S. G. Craig, F. G. Liberante, K. M. Lappin, C. M. Crean, S. S. McDade, A. Thompson, K. Mills, K. I. Savage
This study shows that chronic STAG2 loss alters chromatin structure and deregulates transcription in AML, affecting HOXA and MAPK pathways.
bioRxiv · Nov 26, 2019Cancer Biology