A mechanism of melanogenesis mediated by E-cadherin downregulation and its involvement in solar lentigines
D. Inoue, T. Narita, K. Ishikawa, K. Maeno, A. Motoyama, T. Ono, H. Aoki, T. Shibata
This study identifies E-cadherin downregulation as a mechanism driving melanogenesis in age spots and shows that Rosa multiflora extract can upregulate E-cadherin in keratinocytes.
bioRxiv · Jan 9, 2023Cell Biology