Author

K. O'Byrne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. Kulasinghe· 1 shared A. Pratapa· 1 shared A. Suraweera· 1 shared B. Anand· 1 shared B. Ben Cheikh· 1 shared B. G. M. Hughes· 1 shared C. Cooper· 1 shared C. McIntyre· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. Kulasinghe

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Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivMay 30, 2023

Single-cell Spatial Metabolic and Immune Phenotyping of Head and Neck Cancer Tissues Identifies Tissue Signatures of Response and Resistance to Immunotherapy

N. Jhaveri, B. Ben Cheikh, N. Nikulina…·O. Braubach

This study uses single-cell spatial analysis to identify immune and metabolic tumor microenvironment signatures associated with response and resistance to immunotherapy in head and neck cancer.

DOI 10.1089/genbio.2023.0029

humanspatial transcriptomics

𝕏 PostBluesky

BiochemistrybioRxivMay 21, 2023

Mono-phosphorylation at Ser4 of Barrier-to-autointegration Factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surface

M. Tang, A. Suraweera, X. Nie…·D. J. Richard

This study investigates how mono-phosphorylation at Ser4 of Banf1 disrupts its DNA binding by altering its conformation and binding surface through molecular modeling and simulations.

DOI 10.1039/d3cp02302h

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky

PhysiologybioRxivJun 20, 2021

Urocortin 3 in the posterodorsal medial amygdala mediates psychosocial stress-induced suppression of LH pulsatility in female mice

D. Ivanova, X.-F. Li, C. McIntyre…·K. O'Byrne

This study shows that Urocortin3 in the MePD mediates psychosocial stress-induced suppression of LH pulsatility and CORT release in female mice.

DOI 10.1210/endocr/bqab206

mouseexperimental assay

𝕏 PostBluesky