MHC-II constrains the natural neutralizing antibody response to the SARS-CoV-2 spike RBM in humans
A. Castro, K. Ozturk, M. Zanetti, H. Carter
The paper investigates how MHC-II constraints affect the generation of neutralizing antibodies against the SARS-CoV-2 spike RBM, finding poor peptide binding and potential cross-reactivity with microbial peptides.
bioRxiv · Dec 26, 2020 · PreprintImmunology