SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex
K. P. Stepien, J. Xu, X. Zhang, X. Bai, J. Rizo
The paper reports cryo-EM structures of a Munc18-1-syntaxin-1-synaptobrevin complex, revealing how Munc18-1 facilitates SNARE complex assembly by mediating interactions between syntaxin-1 and synaptobrevin.
bioRxiv · Mar 5, 2022Biophysics