K. S. Jakobsen

Adipose tissue cell states linked to progression and clinical subtypes of MASLD in human obesity

The paper links adipose tissue cell states to progression and clinical subtypes of MASLD in human obesity using single-nucleus RNA sequencing and bulk RNA-seq data.

Genomic repeat landscape evolution across the teleost fish lineages

The paper analyzes repetitive DNA content across 100 teleost fish genomes, finding weak negative correlation between TE content and diversification rates, and independent evolutionary paths for STRs and TEs.

Genomic consequences of range expansion and colonisation in the reed warbler (Acrocephalus scirpaceus)

This study examines the genetic consequences of northward and southward range expansions in reed warblers using RAD-seq, finding little genetic structure and local adaptation to climate variables.

Adaptive protein evolution through length variation in short tandem repeats

The paper shows that length variation in protein regions impacts function and is shaped by natural selection in Arabidopsis thaliana.

Ancient DNA evidence for the ecological globalisation of cod fishing in medieval and post-medieval Europe

This study uses ancient DNA to trace the origins of Atlantic cod specimens from medieval to post-medieval Europe, showing shifts from local to distant sources over time.

Supergenes origin and maintenance in Atlantic cod

The paper investigates the origin and maintenance of four supergenes in Atlantic cod using whole-genome sequencing and long-read data, revealing chromosomal inversions and gene flux mechanisms.

Innovation in NLR and TLR sensing drives the MHC-II free Atlantic cod immune system.

This study identifies NLR and TLR25-based pathways in Atlantic cod's MHC-II free immune system, revealing alternative mechanisms for pathogen recognition and response.

Single cell transcriptome profiling of the Atlantic cod immune system

This study uses single-cell RNA sequencing to characterize the immune system of Atlantic cod, identifying eleven immune cell signatures and proposing gene markers for each.

Metagenomic shotgun analyses reveal complex patterns of intra- and interspecific variation in the intestinal microbiomes of codfishes

The paper uses metagenomic shotgun sequencing to analyze intestinal microbiomes of codfishes, finding that environmental factors drive microbiome variation more than host-specific selection.

Switching on the light: using metagenomic shotgun sequencing to characterize the intestinal microbiome of Atlantic cod

This study uses metagenomic shotgun sequencing to analyze the intestinal microbiome of Atlantic cod, revealing high abundance of Photobacterium species and suggesting a potential ecological role for bioluminescence.

A single Vibrionales 16S rRNA oligotype dominates the intestinal microbiome in two geographically separated Atlantic cod populations

The paper identifies a dominant 16S rRNA oligotype in the gut microbiome of two geographically separated Atlantic cod populations, showing limited spatial segregation and high abundance.