IFNγ and acute prenatal infection with Toxoplasma gondii activate fetal hematopoietic stem cells
D. A. Lopez, K. S. Otsuka, A. C. Apostol, J. Posada, J. C. Sanchez-Arcila, K. D. Jensen, A. E. Beaudin
This study shows that maternal IFNγ and T. gondii infection alter fetal HSC proliferation, self-renewal, and lineage output, with IFNγ mimicking some infection effects.
bioRxiv · Nov 29, 2022 · PreprintImmunology