Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection.
C. Reardon, M. Cremin, V. T. Ramierz, K. Sanchez, E. X. Tay, K. Murray, I. Brust-Mascher
This study shows that blocking Substance P receptor signaling reduces inflammation and prevents maladaptive responses during enteric bacterial infection without affecting host protection.
bioRxiv · Jun 24, 2024Immunology