A chemical screen for suppressors of dioxygenase inhibition in a yeast model of familial paraganglioma
W. Beimers, M. Braun, K. Schwinefus, K. Pearson, B. Wilbanks, L. J. Maher
The paper identifies meclofenoxate HCL and DMAE as suppressors of dioxygenase inhibition in a yeast model of SDH loss by normalizing the succinate:2-ketoglutarate ratio.
bioRxiv · Nov 8, 2021 · PreprintBiochemistry