Direct, sensitive and specific detection of individual single- or double-strand DNA breaks by fluorescence microscopy
M. Kordon, M. Zarebski, K. Solarczyk, H. Ma, T. Pederson, J. W. Dobrucki
The paper introduces STRIDE, a method for detecting single- and double-strand DNA breaks in single cells using fluorescence microscopy, showing higher sensitivity and specificity than existing methods.
bioRxiv · Sep 18, 2019Cell Biology