Positive epistasis for fitness under monosomy: Loss of ribosomal protein stoichiometry reduces the effects of other perturbations
H. Tutaj, K. Tomala, A. Pirog, M. Marszalek, R. Korona
The paper investigates the fitness effects of monosomy in yeast, finding that loss of ribosomal protein stoichiometry reduces the impact of other mutations through positive epistasis.
bioRxiv · Mar 12, 2023Evolutionary Biology