Cancer BiologybioRxiv
Quantitative Imaging of Receptor-Ligand Engagement in Intact Live Animals
A. Rudkouskaya, N. Sinsuebphon, J. Ward…·M. Barroso
This study develops MFLI-FRET to quantify receptor-ligand engagement in live animals, showing it correlates with intracellular ligand binding rather than ex vivo receptor expression.